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- b. May 8, 1939-Montreal, Quebec
-
- Sterling Professor of Biology, Yale University, New Haven, Connecticut
-
- Sid Altman grew up in Montreal but through a twist of fate attended MIT
- where he received a B.Sc. in Physics. He then studied molecular biology
- under Lerman at the University of Colorado Medical School. Lerman helped
- arrange for Altman to go to England to work in the laboratory of S. Brenner
- and F. Crick. While there, in 1970, Altman discovered an unusual enzyme
- involved in the transcription of DNA into protein. He then moved to Yale
- University where his continued research showed that the active part of the
- enzyme consisted of RNA (RiboNucleic Acid). This was significant because
- RNA molecules are much more primitive than protein molecules. Besides
- offering a possible explanation for how life might have begun billions of
- years before proteins existed, it also hints at a way to beat a very
- troublesome primitive life form: the virus for the common cold which is
- based on RNA. It may be possible to design catalytic RNA-based vaccines
- that kill cold viruses by chopping up the RNA on which they are based.
-
- Awards: Nobel Prize in Chemistry, 1989; Rosenstiel Award for Basic
- Biomedical Research, 1989; National Institutes of Health Merit Award, 1989;
- Yale Science and Engineering Assn. Award, 1990
-
- © 1996 Softshell Small Systems Software Design Inc.
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